Enterprise v2.1

Real-Time Multiscale Nephron App
⚡

Kidney Analysis Real-Time

Interactive Real-Time Bio Engine

Live Micro-Nephron View
Blood Toxin Waste
⚠️ High Glomerular Stress
💚
Normal Physiology Stage 1

Hydrostatic pressures stable.

Nephrons 2,000,000
GFR 120 mL/min
Creatinine 1.0 mg/dL
Serum [K+] 4.2 mEq/L

🎛️ Physiological Controls

1:1 Real Time Engine
95 mmHg
90 mg/dL
2300 mg/day
1.0 g/kg/day
100%
0 mg/day
0 cigs/day
0%

📊 Differential Matrix Evaluator

Glomerular Press. (P_gc): 0 mmHg
Oncotic Press. (π_gc): 0 mmHg
Net Pressure (ΔP - Δπ): 0 mmHg
Affer/Effer Resist. (R_A / R_E): 1.00 / 1.00
Real-Time Loss (dN/dt): 0 nephrons/sec
RAAS Hormone Status Baseline (1.0x)
Single Nephron GFR 60 nl/min

📜 Differential Engine State Array

Size: 0/10
Time BP P_gc Nephrons GFR Creatinine [K+]

📘 Simplified Kidney Science Guide

1. Fluid Pressure & Filtering SNGFR = Kf * Net Filter Pressure

High blood pressure pushes fluid into the filter. If pressure drops too low, filtering stops.

2. Valve Squeezing (Afferent Pipe) R_A = Normal Clamp * Drug Factor

The kidney tightens incoming blood vessels to protect filters from high pressure. NSAIDs over-tighten this pipe.

3. Filter Destruction Speed dN/dt = Base Loss + High Pressure + Sugar Loss

Overworked filters break over time. High blood sugar and high pressure speed up filter loss.

4. Toxin Build-Up dC/dt = Protein Intake - Kidney Removal Rate

When filters die, toxic muscle waste (creatinine) and potassium build up in the blood stream.

Macroscopic Kidney Diagram

Renal Cortex (Outer Layer) Renal Pelvis

Microscopic Nephron Diagram

Inflow Pipe Filter Ball Drain Tube